Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24824101 | 0.82 | HRH3 (0.49) | PDK2MAOAMAOBARHRH3 | |
| SCHEMBL18786266 | 0.82 | HRH3 (0.49) | PDK2MAOAMAOBARHRH3 | |
| SCHEMBL6607096 | 0.81 | ALDH1A1 (0.47) | PDK2MAOAMAOBARTP53 | |
| SCHEMBL9417716 | 0.81 | PSEN1 (0.45) | PDK2MAOAMAOBARSMN1; SMN2 | |
| SCHEMBL24681100 | 0.81 | PSEN1 (0.45) | PDK2MAOAMAOBARSMN1; SMN2 | |
| SCHEMBL24681608 | 0.81 | PSEN1 (0.45) | PDK2MAOAMAOBARSMN1; SMN2 | |
| SCHEMBL16480461 | 0.80 | AR (0.50) | PDK2MAOAMAOBARMAPT | |
| SCHEMBL3535701 | 0.80 | MAOA (0.54) | PDK2MAOAMAOBARSMN1; SMN2 | |
| SCHEMBL8284787 | 0.80 | MAOA (0.54) | PDK2MAOAMAOBARSMN1; SMN2 | |
| SCHEMBL20202325 | 0.79 | MAOA (0.43) | PDK2MAOAMAOBARHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884436-B | Benzazepine derivatives and its medical usage | 株式会社三和化学研究所 | 2017-06-13 | — | — | CN | disclosed |