Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151422 | 1.00 | TDP1 (0.53) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28017407 | 0.83 | TDP1 (0.53) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL30992089 | 0.80 | TDP1 (0.55) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL4300665 | 0.80 | TDP1 (0.55) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL12721004 | 0.79 | TDP1 (0.50) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL28196712 | 0.77 | TDP1 (0.57) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL118992 | 0.76 | NPSR1 (0.48) | TDP1LMNAALDH1A1KDM4EGLA | |
| SCHEMBL29556424 | 0.76 | NPSR1 (0.48) | TDP1LMNAALDH1A1KDM4EGLA | |
| SCHEMBL30151412 | 0.75 | TDP1 (0.38) | TDP1HCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL27785159 | 0.75 | TDP1 (0.38) | TDP1HCAR2LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415319-A | Synthesizing aryl carboxylate is coupled by direct Su Chuji | 美国陶氏益农公司 | 2019-03-01 | — | — | CN | claimed |
| CN-102977036-B | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | 美国陶氏益农公司 | 2017-05-03 | — | — | CN | disclosed |