Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 2/20 | 0.33 |
| ▸ | NEK2 | P51955 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.30 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27785159 | 1.00 | TDP1 (0.38) | TDP1ALDH1A1HSD17B10KDM4EKMO | |
| SCHEMBL1397019 | 0.84 | NPSR1 (0.45) | ALDH1A1HSD17B10KDM4EGAASMN1; SMN2 | |
| SCHEMBL27276898 | 0.84 | TPMT (0.39) | TDP1ALDH1A1HSD17B10KDM4EKMO | |
| SCHEMBL30710266 | 0.84 | TPMT (0.39) | TDP1ALDH1A1HSD17B10KDM4EKMO | |
| SCHEMBL28088536 | 0.81 | ALDH1A1 (0.39) | TDP1ALDH1A1HSD17B10KDM4EKMO | |
| SCHEMBL30710300 | 0.80 | KMO (0.39) | TDP1ALDH1A1HSD17B10KDM4EKMO | |
| SCHEMBL31295775 | 0.80 | ALDH1A1 (0.38) | TDP1ALDH1A1HSD17B10KDM4EKMO | |
| SCHEMBL1397016 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EGAASMN1; SMN2 | |
| SCHEMBL1397030 | 0.76 | DHPS (0.54) | ALDH1A1HSD17B10KDM4EKMODHPS | |
| SCHEMBL30151422 | 0.75 | TDP1 (0.53) | TDP1ALDH1A1HSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970185-B1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-07-12 | — | — | EP | disclosed |