Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | CYCS | P99999 | 3/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838442 | 1.00 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL27958997 | 1.00 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL3178604 | 1.00 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL30493184 | 0.95 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL5918884 | 0.95 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL8183442 | 0.90 | TOP1 (0.70) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL9388101 | 0.89 | TOP1 (0.53) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL2141047 | 0.89 | STAT3 (0.63) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL29962487 | 0.86 | TOP1 (0.72) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL30616040 | 0.86 | TOP1 (0.72) | TOP1STAT3STAT1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033153-B | Ornithine modifies amino tetraphenylporphyrin compound and purposes | 中国医学科学院生物医学工程研究所 | 2019-05-21 | — | — | CN | disclosed |
| CN-107033153-A | Ornithine modifies amino tetraphenylporphyrin compound and purposes | 中国医学科学院生物医学工程研究所 | 2017-08-11 | — | — | CN | disclosed |
| CN-103772399-B | Preparation method and use of basic amino acid modified amidotetraphenylporphyrin compound | 中国医学科学院生物医学工程研究所 | 2017-01-25 | — | — | CN | disclosed |