Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | CYCS | P99999 | 3/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838442 | 1.00 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL27958997 | 1.00 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL28149727 | 1.00 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL30493184 | 0.95 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL5918884 | 0.95 | TOP1 (0.55) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL8183442 | 0.90 | TOP1 (0.70) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL9388101 | 0.89 | TOP1 (0.53) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL2141047 | 0.89 | STAT3 (0.63) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL29962487 | 0.86 | TOP1 (0.72) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL30616040 | 0.86 | TOP1 (0.72) | TOP1STAT3STAT1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772399-A | Preparation method and use of basic amino acid modified amidotetraphenylporphyrin compound | INST BIOMEDICAL ENG CAMS | 2014-05-07 | — | — | CN | claimed |
| CN-115925725-A | Aluminum ion fluorescent probe, preparation method and application | 杭州珈晟生物数字技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-108779124-B | Gold porphyrin-PEG conjugates and methods of use | 香港大学 | 2022-03-01 | — | — | CN | disclosed |
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | THE UNIVERSITY OF HONG KONG (HK) | 2021-10-05 | — | — | US | disclosed |
| EP-3386986-B1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | UNIV HONG KONG (CN) | 2021-07-21 | — | — | EP | disclosed |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-08 | — | — | US | disclosed |
| CN-103772399-A | Preparation method and use of basic amino acid modified amidotetraphenylporphyrin compound | INST BIOMEDICAL ENG CAMS | 2014-05-07 | — | — | CN | disclosed |
| US-7655753-B2 | Conjugate | PHOTOBIOTICS LIMITED (GB) | 2010-02-02 | — | — | US | disclosed |
| US-20050234222-A1 | Conjugate | PHOTOBIOTICS LIMITED (GB) | 2005-10-20 | — | — | US | disclosed |
| EP-1416970-A2 | CONJUGATE | Photobiotics Ltd. (GB) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003015825-A2 | CONJUGATE | PHOTOBIOTICS LTD (GB) | 2003-02-27 | — | — | WO | disclosed |
| US-5889181-A | REDUCING NITRO GROUP TO AMINE; DIAZOTIZATION; SULPHONATION;HYDROLYSIS | UNIVERSITY OF SHERBROOKE (CA) | 1999-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | HCCS, PPOX, LIG3 | TOP1 715/4885STAT3 2711/4885STAT1 3130/4885 |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | HCCS, PPOX, LIG3 | TOP1 715/4885STAT3 2711/4885STAT1 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.