Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 4/20 | 0.47 |
| ▸ | CYCS | P99999 | 3/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918884 | 0.90 | TOP1 (0.55) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL30493184 | 0.90 | TOP1 (0.55) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL28838442 | 0.89 | TOP1 (0.55) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL27958997 | 0.89 | TOP1 (0.55) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL28149727 | 0.89 | TOP1 (0.55) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL3178604 | 0.89 | TOP1 (0.55) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL9391899 | 0.86 | TOP1 (0.70) | TOP1TERTCYCSABCG2ENPP2 | |
| SCHEMBL8183442 | 0.85 | TOP1 (0.70) | TOP1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL3912287 | 0.84 | TOP1 (0.58) | TOP1TERTCYCSABCG2ENPP2 | |
| SCHEMBL10141414 | 0.84 | TOP1 (0.58) | TOP1TERTCYCSABCG2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626866-A4 | THE USE OF CAROTENOPORPHYRINS AS TUMOR LOCALIZING AGENTS FOR DIAGNOSIS, VISUALIZATION AND DELIVERY OF SENSITIZERS TO TUMOR TISSUES. | — | 1994-12-21 | — | — | EP | disclosed |
| EP-0626866-A1 | THE USE OF CAROTENOPORPHYRINS AS TUMOR LOCALIZING AGENTS FOR DIAGNOSIS, VISUALIZATION AND DELIVERY OF SENSITIZERS TO TUMOR TISSUES | ARIZONA BOARD OF REGENTS (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1994008631-A1 | THE USE OF CAROTENOPORPHYRINS AS TUMOR LOCALIZING AGENTS FOR DIAGNOSIS, VISUALIZATION AND DELIVERY OF SENSITIZERS TO TUMOR TISSUES | ARIZONA BOARD OF REGENTS (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5286474-A | Use of carotenoporphyrins as tumor localizing agents for diagnosis | ARIZONA BOARD OF REGENTS, A BODY CORPORATE, ACTING FOR AND ON BEHALF THE ARIZONA STATE UNIVERSITY (US) | 1994-02-15 | — | — | US | disclosed |