SCHEMBL28149795

SCHEMBL28149795

CNC1(c2ccc(Cl)c(Cl)c2)CCCC1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 17/20 0.58
SLC6A3 Q01959 17/20 0.58
SLC6A2 P23975 10/20 0.57
KCNH2 Q12809 3/20 0.55
CYP2D6 P10635 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28149780 0.98 SLC6A4 (0.59) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
Hydrochloric Acid SCHEMBL3517561 0.96 KCNH2 (0.59) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
Hydrochloric Acid SCHEMBL11118205 0.95 SLC6A4 (0.57) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
SCHEMBL27734550 0.83 SLC6A3 (0.62) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
SCHEMBL27754805 0.83 SLC6A3 (0.62) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
SCHEMBL11097553 0.83 SLC6A4 (0.62) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
SCHEMBL2238146 0.82 SLC6A4 (0.44) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
SCHEMBL5085610 0.80 SLC6A4 (0.60) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6
SCHEMBL28845096 0.79 SLC6A4 (0.65) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL28148646 0.79 SLC6A4 (0.64) SLC6A4SLC6A3SLC6A2KCNH2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101394847-B Cycloalkylamines as monoamine reuptake inhibitors 塞普拉柯公司 2017-05-24 CN disclosed