Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149795 | 0.83 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL28149780 | 0.81 | SLC6A4 (0.59) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11118205 | 0.81 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL11067006 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL3517561 | 0.80 | KCNH2 (0.59) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL11092837 | 0.79 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2HDAC3HDAC1 | |
| Ethylene SCHEMBL11096036 | 0.79 | SLC6A3 (0.42) | SLC6A4SLC6A3SLC6A2HDAC3HDAC1 | |
| SCHEMBL3519775 | 0.77 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11097091 | 0.76 | SLC6A4 (0.39) | SLC6A4SLC6A3HDAC3HDAC1HDAC2 | |
| SCHEMBL11093629 | 0.75 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |