SCHEMBL28150451

SCHEMBL28150451

CC(O)CC1=CCCOC1=O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.41
TCF4 P15884 2/20 0.32
CTNNB1 P35222 2/20 0.32
CDH1 P12830 1/20 0.32
APC P25054 1/20 0.32
TCF7L2 Q9NQB0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980668 0.75
SCHEMBL4651816 0.72 CYP2C19 (0.37) CYP2C19
SCHEMBL31539187 0.71
SCHEMBL24625081 0.66 SORT1 (0.33)
SCHEMBL7360237 0.64 CYP2C19 (0.55) CYP2C19
SCHEMBL982115 0.63
Propylene Glycol SCHEMBL28566973 0.63 NPC1 (0.35) CYP2C19
Propylene Glycol SCHEMBL28432879 0.63 TDP1 (0.39) CYP2C19
Propylene Glycol SCHEMBL28554703 0.61 TDP1 (0.36) CYP2C19
SCHEMBL4950944 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104402852-B Method for synthesizing natural product Tarchonanthuslactone isomer 江西科技师范大学 2017-05-24 CN disclosed