Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109195 | 0.77 | TAAR1 (0.64) | ALDH1A1TAAR1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL108235 | 0.76 | TAAR1 (0.55) | ALDH1A1HSD17B10TAAR1SLC6A4CYP1A2 | |
| SCHEMBL108109 | 0.75 | TAAR1 (0.62) | ALDH1A1TAAR1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL28393946 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TAAR1SLC6A4CYP1A2 | |
| SCHEMBL4661709 | 0.71 | TAAR1 (0.49) | ALDH1A1HSD17B10TAAR1SLC6A4CYP1A2 | |
| SCHEMBL28115635 | 0.71 | CYP1A2 (0.47) | ALDH1A1HSD17B10TAAR1SLC6A4CYP1A2 | |
| SCHEMBL6132641 | 0.71 | KDM4E (0.54) | ALDH1A1TAAR1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL108065 | 0.71 | CALM1 (0.62) | ALDH1A1TAAR1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL108697 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TAAR1SLC6A4CYP1A2 | |
| SCHEMBL5459105 | 0.70 | TAAR1 (0.56) | ALDH1A1HSD17B10TAAR1SLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699749-B | Application of the 5- piperonyl thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | claimed |
| CN-106699749-A | Application of 5-piperonyl thiazole derivative as anticancer drug | 湖南大学 | 2017-05-24 | — | — | CN | claimed |
| CN-106699749-B | Application of the 5- piperonyl thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-106699749-B | Application of the 5- piperonyl thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-106699749-B | Application of the 5- piperonyl thiazole as anticancer drug | 湖南大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-106699749-A | Application of 5-piperonyl thiazole derivative as anticancer drug | 湖南大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699749-A | Application of 5-piperonyl thiazole derivative as anticancer drug | 湖南大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699749-A | Application of 5-piperonyl thiazole derivative as anticancer drug | 湖南大学 | 2017-05-24 | — | — | CN | disclosed |