SCHEMBL28150484

SCHEMBL28150484

O=C(O)c1cccc(C(=O)c2ccccc2)c1-c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.64
CDC25B P30305 2/20 0.61
ATM Q13315 2/20 0.61
HNF4A P41235 1/20 0.52
MAPT P10636 2/20 0.50
KDM4E B2RXH2 2/20 0.50
NR4A1 P22736 1/20 0.50
GAA P10253 1/20 0.50
POLB P06746 1/20 0.50
ALDH1A1 P00352 3/20 0.49
ALOX15 P16050 1/20 0.48
ADORA1 P30542 1/20 0.47
CDC25A P30304 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SRD5A2 P31213 1/20 0.47
PIM1 P11309 1/20 0.46
GFER P55789 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL934810 0.94 AKR1C3 (0.59) AKR1C3CDC25BATMHNF4AMAPT
SCHEMBL70098 0.88 HNF4A (0.63) CDC25BATMHNF4AMAPTKDM4E
SCHEMBL28391136 0.84 HNF4A (0.59) CDC25BATMHNF4AMAPTKDM4E
SCHEMBL2333980 0.83 ALDH1A1 (0.56) AKR1C3CDC25BATMHNF4AMAPT
SCHEMBL92724 0.83 AKR1C3 (0.52) AKR1C3CDC25BATMHNF4AMAPT
SCHEMBL30618783 0.83 ALDH1A1 (0.56) AKR1C3CDC25BATMHNF4AMAPT
SCHEMBL27985225 0.81 MAPT (0.67) AKR1C3CDC25BATMMAPTGAA
SCHEMBL27851949 0.81 FABP3 (0.54) AKR1C3CDC25BATMMAPTNR4A1
SCHEMBL1505897 0.81 TTR (0.53) AKR1C3CDC25BATMMAPTGAA
SCHEMBL17955078 0.80 AKR1C3 (0.48) AKR1C3CDC25BATMMAPTNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106892814-B A kind of preparation method of neighbour's sweet-smelling formacyl benzoic ether 北京英力科技发展有限公司 2019-07-02 CN disclosed
CN-106892814-A A kind of preparation method of adjacent sweet-smelling formacyl benzoic ether 北京英力科技发展有限公司 2017-06-27 CN disclosed