SCHEMBL28150548

SCHEMBL28150548

NCCC(N)NC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.38
TP53 P04637 1/20 0.35
ANPEP P15144 2/20 0.35
ERAP2 Q6P179 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 2/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ADRB2 P07550 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8967551 0.86 SIGMAR1 (0.39) EPHX1TP53ANPEPERAP2
SCHEMBL28080788 0.81 SMN1; SMN2 (0.39) EPHX1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL3138483 0.78 EPHX1 (0.41) EPHX1ALDH1A1
SCHEMBL9810149 0.77 EPHX1 (0.41) EPHX1TP53ANPEPERAP2ALDH1A1
SCHEMBL16949689 0.76 SIGMAR1 (0.44) EPHX1ALDH1A1
SCHEMBL4528804 0.76 SIGMAR1 (0.44) EPHX1ALDH1A1
SCHEMBL4751060 0.76 EPHX2 (0.38) ANPEPERAP2ALDH1A1HSD17B10KDM4E
SCHEMBL20540216 0.76 SIGMAR1 (0.44) EPHX1ALDH1A1
SCHEMBL8949667 0.76 SIGMAR1 (0.44) EPHX1ALDH1A1
SCHEMBL460663 0.76 SHBG (0.44) EPHX1ANPEPERAP2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866431-A A kind of production method of 1,3 propane diamine of N (2 methoxycyclohexyl) 浙江新化化工股份有限公司 2017-06-20 CN claimed