Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ESRRG | P62508 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150648 | 1.00 | PKM (0.48) | PKMALDH1A1RXFP1MAPTGFER | |
| SCHEMBL28150658 | 0.93 | MAPT (0.52) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150661 | 0.93 | MAPT (0.52) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150642 | 0.91 | KMT2A (0.45) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150791 | 0.91 | NPC1 (0.50) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150790 | 0.91 | NPC1 (0.50) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150779 | 0.91 | KMT2A (0.48) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150782 | 0.91 | KMT2A (0.48) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28150647 | 0.91 | KMT2A (0.45) | PKMALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28845327 | 0.91 | NPC1 (0.52) | PKMALDH1A1MAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749135-B | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2019-07-19 | — | — | CN | disclosed |
| CN-106749135-A | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2017-05-31 | — | — | CN | disclosed |