Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150661 | 1.00 | MAPT (0.52) | MAPTPKMNPC1RAB9AGAA | |
| SCHEMBL28150650 | 0.93 | PKM (0.48) | MAPTPKMNPC1RAB9AKDM4E | |
| SCHEMBL28150648 | 0.93 | PKM (0.48) | MAPTPKMNPC1RAB9AKDM4E | |
| SCHEMBL28150779 | 0.91 | KMT2A (0.48) | MAPTPKMNPC1RAB9AKDM4E | |
| SCHEMBL28150791 | 0.91 | NPC1 (0.50) | MAPTPKMNPC1RAB9AGAA | |
| SCHEMBL28150642 | 0.91 | KMT2A (0.45) | MAPTPKMNPC1RAB9AKDM4E | |
| SCHEMBL28150782 | 0.91 | KMT2A (0.48) | MAPTPKMNPC1RAB9AKDM4E | |
| SCHEMBL28150647 | 0.91 | KMT2A (0.45) | MAPTPKMNPC1RAB9AKDM4E | |
| SCHEMBL28150790 | 0.91 | NPC1 (0.50) | MAPTPKMNPC1RAB9AGAA | |
| SCHEMBL28845327 | 0.91 | NPC1 (0.52) | MAPTPKMNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749135-B | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2019-07-19 | — | — | CN | disclosed |
| CN-106749135-A | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2017-05-31 | — | — | CN | disclosed |