SCHEMBL28150950

SCHEMBL28150950

COc1cccc(C(N)F)c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 3/20 0.51
TAAR1 Q96RJ0 3/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP3A4 P08684 1/20 0.50
ACHE P22303 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CASR P41180 2/20 0.45
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.43
PARP1 P09874 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15271036 0.83 CASR (0.51) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL10781776 0.83 AOC3 (0.54) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL10781087 0.83 AOC3 (0.54) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL29676707 0.82 TAAR1 (0.56) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL335622 0.82 TAAR1 (0.56) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL29350839 0.82 TAAR1 (0.56) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL135107 0.82 TAAR1 (0.56) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL335349 0.82 TAAR1 (0.56) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
SCHEMBL30617765 0.82 TAAR1 (0.56) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4
Hydrochloric Acid SCHEMBL12495550 0.80 TAAR1 (0.55) AOC3TAAR1ALDH1A1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105407724-B Process for preparing 4-amino-3-halo-6- (substituted) picolinates and 4-amino-5-fluoro-3-halo-6- (substituted) picolinates 美国陶氏益农公司 2017-06-09 CN disclosed