Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 14/20 | 0.72 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.60 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892955 | 0.92 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL27798484 | 0.89 | KCNN4 (0.64) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL830791 | 0.87 | MAPT (0.60) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL2337394 | 0.84 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| Senicapoc SCHEMBL1443805 | 0.84 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL5056595 | 0.81 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL28151671 | 0.81 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL27639725 | 0.78 | KCNN4 (0.64) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL12811863 | 0.78 | KCNN4 (0.86) | KCNN4KCNE1KCNQ1KIF11NPC1 | |
| SCHEMBL13241625 | 0.76 | CA1 (0.52) | KCNN4KCNE1KCNQ1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970759-A | The inhibitor of protein tyrosine kinase activity | 梅特希尔基因公司 | 2019-07-05 | — | — | CN | disclosed |