Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162987 | 0.81 | NR1H4 (0.58) | NR1H4LMNAPOLB | |
| SCHEMBL30619395 | 0.81 | NR1H4 (0.58) | NR1H4LMNAPOLB | |
| SCHEMBL9863289 | 0.81 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1MEN1NPC1 | |
| SCHEMBL194382 | 0.80 | NR1H4 (0.56) | NR1H4 | |
| SCHEMBL27668540 | 0.79 | LMNA (0.46) | NR1H4LMNAPOLBALDH1A1TSHR | |
| SCHEMBL9706872 | 0.79 | LMNA (0.46) | NR1H4LMNAPOLBALDH1A1TSHR | |
| SCHEMBL13980716 | 0.78 | POLB (0.50) | LMNAPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL29991524 | 0.78 | POLB (0.50) | LMNAPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL18295333 | 0.78 | LMNA (0.45) | NR1H4LMNAPOLBALDH1A1MAPT | |
| SCHEMBL27816499 | 0.78 | LMNA (0.45) | NR1H4LMNAPOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304551-B | Hepatitis AG14361 | 北京凯因科技股份有限公司 | 2017-06-13 | — | — | CN | disclosed |