Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393411 | 0.80 | — | — | |
| SCHEMBL26025316 | 0.80 | OPRM1 (0.48) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL19596576 | 0.80 | OPRM1 (0.48) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL12082030 | 0.80 | GRIK1 (0.52) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL14819881 | 0.80 | GRIK1 (0.52) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL14605594 | 0.80 | OPRM1 (0.48) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL18392189 | 0.80 | GRIK1 (0.52) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL28348793 | 0.79 | SPHK1 (0.54) | OPRM1SPHK1TP53LAP3GRIK1 | |
| Hydrochloric Acid SCHEMBL1512461 | 0.78 | GRIK1 (0.50) | OPRM1SPHK1TP53LAP3GRIK1 | |
| SCHEMBL4658553 | 0.78 | GRIK1 (0.53) | OPRM1SPHK1TP53LAP3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108175749-A | The solid dispersions of melt extrusion containing cell death inducer | 艾伯维爱尔兰无限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-103282025-B | Melt-extruded solid dispersions containing apoptosis-inducing agents | 艾伯维爱尔兰无限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107108552-A | Heterocyclic kinase inhibitors | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-104876927-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2017-06-23 | — | — | CN | disclosed |