Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189410 | 1.00 | PDK1 (0.49) | PDK1PDK2PDK3TLR9TLR8 | |
| SCHEMBL28127144 | 1.00 | PDK1 (0.49) | PDK1PDK2PDK3TLR9TLR8 | |
| SCHEMBL28153082 | 0.84 | PDK1 (0.37) | PDK1PDK2PDK3 | |
| SCHEMBL24630698 | 0.81 | PDK1 (0.51) | PDK1PDK2PDK3 | |
| SCHEMBL17778486 | 0.81 | PDK1 (0.51) | PDK1PDK2PDK3 | |
| SCHEMBL1700062 | 0.81 | PDK1 (0.51) | PDK1PDK2PDK3 | |
| SCHEMBL23588706 | 0.77 | PDK1 (0.45) | PDK1PDK2PDK3 | |
| SCHEMBL14944367 | 0.77 | PDK1 (0.51) | PDK1PDK2PDK3 | |
| SCHEMBL24801874 | 0.77 | PDK1 (0.51) | PDK1PDK2PDK3 | |
| SCHEMBL21369290 | 0.77 | PDK1 (0.51) | PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876927-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2017-06-23 | — | — | CN | disclosed |