Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AMD1 | P17707 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960127 | 0.80 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18518449 | 0.78 | POLB (0.42) | ALDH1A1MAPTTP53CYP3A4TSHR | |
| SCHEMBL8283885 | 0.77 | MAPT (0.63) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL16727185 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL24683493 | 0.76 | CYP2C9 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18518470 | 0.74 | POLB (0.38) | ALDH1A1MAPTTP53CYP3A4TSHR | |
| SCHEMBL4322451 | 0.74 | MAOB (0.62) | — | |
| SCHEMBL13191751 | 0.74 | MAPT (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1401588 | 0.74 | TSHR (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL15334232 | 0.73 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928126-B | Amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-106928126-A | A kind of amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |