SCHEMBL28153306

SCHEMBL28153306

CCCCNC=C(C)C=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 3/20 0.54
ADH1A P07327 3/20 0.54
ADH7 P40394 3/20 0.54
ADH1C P00326 2/20 0.54
EPHX1 P07099 3/20 0.46
ADH4 P08319 1/20 0.46
TSHR P16473 4/20 0.37
ALOX15 P16050 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PAOX Q6QHF9 1/20 0.32
ACHE P22303 1/20 0.32
MMP2 P08253 1/20 0.32
HDAC3 O15379 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28160614 0.92 EPHX1 (0.59) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL28218181 0.92 EPHX1 (0.59) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL28179459 0.92 EPHX1 (0.59) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL28155463 0.86
Hydrochloric Acid SCHEMBL28847916 0.84 ADH1B (0.48) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL21517812 0.78 ACHE (0.38) ADH1BADH1AADH7ADH1CTSHR
SCHEMBL28207499 0.77
SCHEMBL23736635 0.77 ADH1B (0.52) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL21098611 0.77 ADH1B (0.41) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL28566561 0.77 ADH1B (0.52) ADH1BADH1AADH7ADH1CEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106748988-B A kind of method that supercritical ultrasonics technology synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate 山东师范大学 2019-05-28 CN claimed
CN-106866515-B A kind of sulfonyl pyridine derivative and its synthetic method 山东师范大学 2019-05-28 CN claimed
CN-106518757-B A kind of method that microwave method synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate 山东师范大学 2019-03-19 CN claimed
CN-106866515-A A kind of sulfonyl pyridine derivative and its synthetic method 山东师范大学 2017-06-20 CN claimed
CN-106831551-A A kind of method of the ionic liquid method synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate 山东师范大学 2017-06-13 CN claimed
CN-106831551-B A kind of method that ionic liquid method synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate 山东师范大学 2019-09-24 CN disclosed
CN-106748988-B A kind of method that supercritical ultrasonics technology synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate 山东师范大学 2019-05-28 CN disclosed
CN-106866515-B A kind of sulfonyl pyridine derivative and its synthetic method 山东师范大学 2019-05-28 CN disclosed
CN-106866514-B A kind of method that Aqueous phase synthesizes the halogenated -3- substituted hydrocarbon radical sulfonyl pyridine of 2- and its intermediate 山东师范大学 2019-05-28 CN disclosed
CN-106866515-A A kind of sulfonyl pyridine derivative and its synthetic method 山东师范大学 2017-06-20 CN disclosed
CN-106866514-A A kind of method of the Aqueous phase synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate 山东师范大学 2017-06-20 CN disclosed
CN-106831551-A A kind of method of the ionic liquid method synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate 山东师范大学 2017-06-13 CN disclosed
CN-106748988-A A kind of method of the supercritical ultrasonics technology synthesis substituted hydrocarbon radical sulfonyl pyridine of 2 halo 3 and its intermediate 山东师范大学 2017-05-31 CN disclosed