Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | CD38 | P28907 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831069 | 1.00 | PARP1 (0.74) | PARP1KDM4EGAAMAPTMETAP2 | |
| SCHEMBL29923839 | 0.85 | PARP1 (1.00) | PARP1GAAMAPTMETAP2CD38 | |
| SCHEMBL422282 | 0.85 | PARP1 (1.00) | PARP1GAAMAPTMETAP2CD38 | |
| SCHEMBL29831074 | 0.82 | PARP1 (0.65) | PARP1KDM4EGAAMAPTMETAP2 | |
| SCHEMBL2115749 | 0.80 | CCR1 (0.64) | PARP1KDM4EGAAMAPTMETAP2 | |
| SCHEMBL28199876 | 0.78 | PARP1 (0.73) | PARP1KDM4EMAPTMETAP2BCAT2 | |
| SCHEMBL29831065 | 0.77 | PARP1 (0.55) | PARP1KDM4EGAAMAPTMETAP2 | |
| SCHEMBL29102039 | 0.77 | PARP1 (0.55) | PARP1KDM4EGAAMAPTMETAP2 | |
| SCHEMBL30514077 | 0.74 | BCAT2 (0.74) | PARP1KDM4EGAAMAPTMETAP2 | |
| SCHEMBL210767 | 0.74 | BCAT2 (0.74) | PARP1KDM4EGAAMAPTMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106966973-A | N phenyl N（The quinolyl of 2 methyl 8）The preparation method of benzamide | 湖北工业大学 | 2017-07-21 | — | — | CN | disclosed |