Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28845596 | 0.98 | DPP4 (0.52) | DPP4DPP8PLA2G7PNMTMGAM | |
| SCHEMBL1127909 | 0.82 | TAAR1 (0.52) | DPP4PNMTGAA | |
| SCHEMBL3790197 | 0.79 | DPP4 (0.50) | DPP4DPP8PNMT | |
| SCHEMBL16814934 | 0.77 | DPP4 (0.50) | DPP4DPP8 | |
| SCHEMBL2482119 | 0.77 | DPP4 (0.50) | DPP4DPP8 | |
| SCHEMBL2232919 | 0.76 | PLA2G7 (0.53) | DPP4PLA2G7MGAMGAASI | |
| SCHEMBL321560 | 0.75 | PLA2G7 (0.61) | DPP4PLA2G7MGAMGAASI | |
| SCHEMBL16814912 | 0.75 | DPP4 (0.47) | DPP4DPP8POLB | |
| SCHEMBL394915 | 0.75 | CYP1A2 (0.43) | DPP4 | |
| SCHEMBL23198751 | 0.74 | PLA2G7 (0.50) | DPP4PLA2G7MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610262-B | Biphenyl compound, intermediate, preparation method, pharmaceutical composition and its application | 上海医药工业研究院 | 2017-06-06 | — | — | CN | disclosed |