Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28154356

F[P-](F)(F)(F)(F)F.S.[H+].c1ccc(-c2ccsc2)cc1

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.75
CYP2B6 P20813 3/20 0.75
CYP2E1 P05181 2/20 0.75
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
GLO1 Q04760 1/20 0.42
PDGFRB P09619 2/20 0.40
PDGFRA P16234 2/20 0.40
PTPRC P08575 1/20 0.40
CDK8 P49336 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
KCNH2 Q12809 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
CYP17A1 P05093 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
ALDH1A1 P00352 1/20 0.38
FYN P06241 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149952 0.87 CYP2A6 (1.00) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL24106775 0.84 CYP2A6 (0.95) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL3997707 0.79
SCHEMBL28164029 0.78 CYP2A6 (0.82) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
Biphenyl SCHEMBL27786847 0.76 ALDH1A1 (0.64) CYP2A6CYP2B6CYP2E1CYP3A4ALDH1A1
SCHEMBL27811941 0.75 CYP2A6 (0.75) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL27989815 0.74 CYP2A6 (0.74) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL2125063 0.74 CYP2A6 (0.72) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL5477270 0.72 CYP2A6 (0.69) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL7058734 0.71 CYP2A6 (0.70) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104395422-B Radical curable adhesive composition and polarizing plate including the same LG化学株式会社 2017-05-24 CN disclosed