Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315500 | 0.88 | POLB (0.50) | LMNAMAPK1HTTRAB9A | |
| SCHEMBL436124 | 0.83 | CYP4F2 (0.47) | MTNR1AMTNR1B | |
| SCHEMBL30873959 | 0.81 | POLB (0.50) | LMNAMAPK1HTTRAB9A | |
| SCHEMBL14441618 | 0.79 | POLB (0.51) | MTNR1AMTNR1B | |
| SCHEMBL20185961 | 0.79 | HDAC1 (0.44) | — | |
| SCHEMBL584254 | 0.78 | ALDH1A1 (0.42) | ALOX5LMNA | |
| SCHEMBL20969693 | 0.78 | TAAR1 (0.53) | HTR2B | |
| SCHEMBL11919300 | 0.77 | TAAR1 (0.47) | HTR2BMTNR1AMTNR1BLMNAMAPK1 | |
| SCHEMBL584610 | 0.77 | TNKS2 (0.45) | HTR2BALOX5MTNR1AMTNR1BLMNA | |
| SCHEMBL3409461 | 0.77 | HSD17B10 (0.51) | MTNR1AMTNR1BLMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906617-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-104254534-B | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-105906617-A | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2016-08-31 | — | — | CN | disclosed |