SCHEMBL20969693

SCHEMBL20969693

COc1cc(F)c(CCN)cc1F

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.53
HTR2A P28223 6/20 0.50
HTR2C P28335 3/20 0.50
ADRA1A P35348 1/20 0.50
CYP1A2 P05177 1/20 0.49
HTR2B P41595 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7273672 0.88 HTR2A (0.58) TAAR1HTR2AHTR2CHTR2B
SCHEMBL29473870 0.88 TAAR1 (0.69) TAAR1HTR2AHTR2CHTR2B
SCHEMBL1047458 0.88 TAAR1 (0.69) TAAR1HTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL26096716 0.86 TAAR1 (0.67) TAAR1HTR2AHTR2CHTR2B
SCHEMBL34463042 0.86 TAAR1 (0.66) TAAR1HTR2AHTR2CADRA1AHTR2B
SCHEMBL20562467 0.86 TAAR1 (0.66) TAAR1HTR2AHTR2CADRA1AHTR2B
SCHEMBL584610 0.79 TNKS2 (0.45) HTR2B
SCHEMBL11919300 0.79 TAAR1 (0.47) TAAR1HTR2AHTR2CHTR2B
SCHEMBL585104 0.78 ALDH1A1 (0.38) TAAR1
SCHEMBL28154665 0.78 HTR2B (0.43) HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3483149-B1 BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME YUHAN CORP (KR) 2021-01-13 EP disclosed
US-10383859-B2 Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same YUHAN CORPORATION (KR) 2019-08-20 US disclosed
US-20190142809-A1 Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same YUHAN CORPORATION (KR) 2019-05-16 US disclosed
EP-3483149-A1 BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Yuhan Corporation (KR) 2019-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142809-A1 Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same ILK, SBDS, BDKRB1 TAAR1 3745/4885HTR2A 4659/4885HTR2C 4702/4885
US-10383859-B2 Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same ILK, SBDS, BDKRB1 TAAR1 3745/4885HTR2A 4659/4885HTR2C 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.