Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818031 | 0.92 | ROCK1 (0.46) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2819890 | 0.87 | ROCK1 (0.46) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27775769 | 0.83 | ROCK1 (0.47) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2816746 | 0.79 | NPC1 (0.45) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2818047 | 0.76 | LCK (0.45) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4555774 | 0.75 | NTRK1 (0.51) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4555775 | 0.74 | NTRK1 (0.51) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2819798 | 0.73 | RAB9A (0.56) | MEN1KMT2ARAB9ANPC1NQO2 | |
| SCHEMBL4442283 | 0.72 | KMT2A (0.47) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL2816881 | 0.72 | RAB9A (0.54) | MEN1KMT2ARAB9ANPC1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | ROCK1 2031/4885MEN1 150/4885KMT2A 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.