Urea

Urea

SCHEMBL28155135

NC(N)=O.NNC(=O)NN

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
NFKB1 P19838 2/20 0.57
CYP1A2 P05177 1/20 0.57
MAOA P21397 1/20 0.57
MAOB P27338 1/20 0.57
THPO P40225 1/20 0.57
LMNA P02545 4/20 0.53
ALDH1A1 P00352 2/20 0.50
OR51E2 Q9H255 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
BLM P54132 2/20 0.38
PMP22 Q01453 2/20 0.38
PTGS2 P35354 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA2 P00918 1/20 0.38
CYP3A4 P08684 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
HIF1A Q16665 1/20 0.37
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623380 0.91 NFKB1 (0.54) TSHRNFKB1CYP1A2MAOAMAOB
SCHEMBL64716 0.91
SCHEMBL20178517 0.91 NFKB1 (0.54) TSHRNFKB1CYP1A2MAOAMAOB
Carbamic Acid SCHEMBL27643073 0.88 ACHE (0.54) TSHRNFKB1CYP1A2MAOAMAOB
SCHEMBL1537923 0.87
Potassium SCHEMBL18585217 0.87
Hydrochloric Acid SCHEMBL6335251 0.87
Hydrochloric Acid SCHEMBL4489744 0.87
Water SCHEMBL7464138 0.87
SCHEMBL8017494 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105358633-B Intumescent coating composition 阿克佐诺贝尔国际涂料股份有限公司 2017-07-21 CN disclosed