Pyrimidine

Pyrimidine

SCHEMBL28155232

O=S(O)O.c1cncnc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL28540377 0.89 CA1 (0.32) CA1CA2
Pyrimidine SCHEMBL27657662 0.86 TSHR (0.38) TSHRNAPRTTDP1CYP2A6
Sulfurous Acid SCHEMBL6705052 0.82 CA1 (0.50) CA1CA2
Pyridine SCHEMBL17688281 0.80 NAPRT (0.60) CA1CA2TSHRNAPRTTDP1
Pyridine SCHEMBL11789826 0.80 NAPRT (0.60) CA1CA2TSHRNAPRTTDP1
Pyrimidine SCHEMBL27525015 0.80 TSHR (0.33) TSHRNAPRTTDP1CYP2A6
Pyridine SCHEMBL27837604 0.80 NAPRT (0.60) CA1CA2TSHRNAPRTTDP1
Pyrimidine SCHEMBL27818622 0.78 TSHR (0.54) TSHRNAPRTTDP1CYP2A6
Pyrimidine SCHEMBL10646 0.78 TSHR (0.50) TSHRNAPRTTDP1CYP2A6
Pyrimidine SCHEMBL1846 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108350504-A The diagnostic method of carcinoma of urinary bladder UCL商业有限公司 2018-07-31 CN disclosed
CN-106854679-A Methylate DNA detection method 广州市基准医疗有限责任公司 2017-06-16 CN disclosed
CN-106755319-A Methylate DNA detection method 广州市基准医疗有限责任公司 2017-05-31 CN disclosed