Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091641 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL557204 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL20567660 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL4538607 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL2183439 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL4540684 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL1745096 | 0.86 | PPARA (0.58) | PPARATSHRGAAPLA2G4BTP53 | |
| SCHEMBL27305573 | 0.84 | TSHR (0.56) | TSHRALDH1A1HSD17B10TDP1PLA2G4B | |
| SCHEMBL7814103 | 0.81 | MAPT (0.70) | PPARATSHRTDP1GAAPLA2G4B | |
| SCHEMBL27302733 | 0.81 | TSHR (0.56) | TSHRALDH1A1HSD17B10TDP1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104519902-B | Double acylated GLP-1 derivatives | 诺和诺德股份有限公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-107266558-A | The derivatives of GLP 1 | 诺沃—诺迪斯克有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-104411322-B | Double acylated GLP-1 derivatives | 诺和诺德股份有限公司 | 2017-05-24 | — | — | CN | disclosed |