Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745096 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL26091641 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL2183439 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL20567660 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL4538607 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL557204 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL1363883 | 0.92 | PPARA (0.51) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL28155239 | 0.86 | PPARA (0.56) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL1743906 | 0.86 | MAPT (0.53) | GAATP53TSHRL3MBTL1HDAC1 | |
| SCHEMBL558993 | 0.86 | MAPT (0.53) | GAATP53TSHRL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518795-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2022-12-06 | — | — | US | disclosed |
| EP-2637698-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK AS (DK) | 2022-04-20 | — | — | EP | disclosed |
| US-11274135-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2022-03-15 | — | — | US | disclosed |
| US-20200123215-A1 | Double-Acylated GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2020-04-23 | — | — | US | disclosed |
| US-10604554-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2020-03-31 | — | — | US | disclosed |
| US-10308700-B2 | GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2019-06-04 | — | — | US | disclosed |
| US-20180244742-A1 | Double-Acylated GLP-1 Derivatives | NOVO NORDISK AS (DK) | 2018-08-30 | — | — | US | disclosed |
| US-10000542-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2018-06-19 | — | — | US | disclosed |
| EP-2637699-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER | NOVO NORDISK AS (DK) | 2018-05-16 | — | — | EP | disclosed |
| US-9758560-B2 | GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2017-09-12 | — | — | US | disclosed |
| US-20140303083-A1 | GLP-1 Derivatives | NOVO NORDISK A/S (DK) | 2014-10-09 | — | — | US | disclosed |
| US-20130338068-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER | NOVO NORDISK A/S (DK) | 2013-12-19 | — | — | US | disclosed |
| WO-2013167455-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK A/S (DK) | 2013-11-14 | — | — | WO | disclosed |
| WO-2013167454-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK A/S (DK) | 2013-11-14 | — | — | WO | disclosed |
| US-20130288960-A1 | Double-Acylated GLP-1 Derivatives | NOVO NORDISK A/S (DK) | 2013-10-31 | — | — | US | disclosed |
| EP-2637699-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER | Novo Nordisk A/S (DK) | 2013-09-18 | — | — | EP | disclosed |
| EP-2637698-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | Novo Nordisk A/S (DK) | 2013-09-18 | — | — | EP | disclosed |
| WO-2013037690-A1 | GLP-1 DERIVATIVES | NOVO NORDISK A/S (DK) | 2013-03-21 | — | — | WO | disclosed |
| WO-2012062803-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK A/S (DK) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062804-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER | NOVO NORDISK A/S (DK) | 2012-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604554-B2 | Double-acylated GLP-1 derivatives | GLP1R, GIPR, GPR119 | PPARA 382/4885GAA 4655/4885PLA2G4B 3166/4885 |
| US-20180244742-A1 | Double-Acylated GLP-1 Derivatives | GLP1R, GIPR, GPR119 | PPARA 390/4885GAA 4646/4885PLA2G4B 3159/4885 |
| US-20140303083-A1 | GLP-1 Derivatives | GLP1R, GIPR, GCG | PPARA 2489/4885GAA 4183/4885PLA2G4B 3786/4885 |
| US-10308700-B2 | GLP-1 derivatives | GLP1R, GIPR, GCG | PPARA 1869/4885GAA 4180/4885PLA2G4B 3693/4885 |
| US-11274135-B2 | Double-acylated GLP-1 derivatives | GLP1R, GIPR, GPR119 | PPARA 341/4885GAA 4653/4885PLA2G4B 3291/4885 |
| US-10000542-B2 | Double-acylated GLP-1 derivatives | GLP1R, GIPR, GPR119 | PPARA 382/4885GAA 4655/4885PLA2G4B 3166/4885 |
| US-20130288960-A1 | Double-Acylated GLP-1 Derivatives | GLP1R, VIP, IAPP | PPARA 1006/4885GAA 4245/4885PLA2G4B 3823/4885 |
| US-20130338068-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER | GLP1R, VIP, IAPP | PPARA 1163/4885GAA 3847/4885PLA2G4B 4078/4885 |
| US-20200123215-A1 | Double-Acylated GLP-1 Derivatives | GLP1R, GIPR, GPR119 | PPARA 382/4885GAA 4655/4885PLA2G4B 3166/4885 |
| US-11518795-B2 | Double-acylated GLP-1 derivatives | GLP1R, GIPR, GPR119 | PPARA 382/4885GAA 4655/4885PLA2G4B 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.