Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21189088 | 0.89 | TSHR (0.44) | TSHRALDH1A1ATMEGLN2ADRA2A | |
| SCHEMBL28330142 | 0.80 | MMP3 (0.55) | ALDH1A1EGLN2HTTHSD17B10KDM4E | |
| SCHEMBL2153449 | 0.79 | TTR (0.44) | TSHRALDH1A1EGLN2HSD17B10KDM4E | |
| SCHEMBL20608469 | 0.79 | METAP2 (0.46) | TSHRALDH1A1ATMADORA2AHSD17B10 | |
| SCHEMBL24580808 | 0.78 | GRM5 (0.52) | ALDH1A1EGLN2HSD17B10L3MBTL1 | |
| SCHEMBL30703107 | 0.78 | GRM5 (0.52) | ALDH1A1EGLN2HSD17B10L3MBTL1 | |
| SCHEMBL20873646 | 0.77 | MAPT (0.43) | TSHRALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL16050408 | 0.77 | TSHR (0.60) | TSHRADORA2AMETAP2ABCG2 | |
| SCHEMBL20740870 | 0.77 | METAP2 (0.51) | TSHRALDH1A1ATMFASNADORA2A | |
| SCHEMBL18411450 | 0.77 | TSHR (0.48) | TSHRALDH1A1FASNHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831773-A | Compound containing 9, 9' -spiroacridine and preparation method and application thereof | 华南理工大学 | 2017-06-13 | — | — | CN | disclosed |