Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132364 | 0.89 | TSHR (0.67) | TSHRALDH1A1TP53LMNACES2 | |
| SCHEMBL20346867 | 0.88 | ALDH1A1 (0.59) | TSHRALDH1A1TP53LMNAPAOX | |
| Acetic Acid SCHEMBL10816374 | 0.88 | TSHR (0.67) | TSHRALDH1A1TP53LMNAPAOX | |
| Acetone SCHEMBL28159547 | 0.87 | TSHR (0.90) | TSHRALDH1A1TP53CES2CES1 | |
| Hydrochloric Acid SCHEMBL7947881 | 0.86 | TSHR (0.63) | TSHRALDH1A1TP53LMNACES2 | |
| SCHEMBL2154041 | 0.86 | TSHR (0.72) | TSHRALDH1A1TP53LMNACES2 | |
| SCHEMBL6057206 | 0.86 | TSHR (0.72) | TSHRALDH1A1TP53LMNACES2 | |
| SCHEMBL496221 | 0.86 | TSHR (0.72) | TSHRALDH1A1TP53LMNACES2 | |
| SCHEMBL466419 | 0.86 | TSHR (0.72) | TSHRALDH1A1TP53LMNACES2 | |
| SCHEMBL7329781 | 0.86 | TSHR (0.72) | TSHRALDH1A1TP53LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104857556-B | A kind of chemical graft type long-acting slow-release anti-bacteria real silk suture and preparation method thereof | 东华大学 | 2017-06-06 | — | — | CN | disclosed |