Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL495403 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL494763 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL6057206 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL494288 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL466419 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL495310 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL496221 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154041 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154814 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154590 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616606-A | DISTAMYCIN DERIVATIVES; DEACTIVATION OF NUCLEIC ACIDS BY BINDING WITH NO STERIC HINDRANCE PROBLEMS; HIV AND HEPATITUS VIRUS | SYNPHAR LABORATORIES, INC. (CA) | 1997-04-01 | — | — | US | disclosed |
| WO-1995004732-A1 | OLIGOPEPTIDE ANTIRETROVIRAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1995-02-16 | — | — | WO | disclosed |
| WO-1992013838-A1 | OLIGOPEPTIDE ANTIRETROVIRAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1992-08-20 | — | — | WO | disclosed |