Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750976 | 0.84 | TLR8 (0.49) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| SCHEMBL6982374 | 0.83 | TLR8 (0.47) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| SCHEMBL27725467 | 0.83 | TLR8 (0.47) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| SCHEMBL28020387 | 0.83 | TLR8 (0.47) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| SCHEMBL11401202 | 0.83 | TLR8 (0.47) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8582822 | 0.81 | TLR8 (0.46) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| SCHEMBL8049756 | 0.80 | BACE1 (0.49) | BACE1TLR8TLR7TDP1L3MBTL1 | |
| SCHEMBL28906708 | 0.75 | TLR8 (0.42) | BACE1TLR8TLR7LIPG | |
| SCHEMBL2384178 | 0.73 | BACE1 (0.51) | BACE1TLR8TDP1TKT | |
| SCHEMBL111622 | 0.73 | MIF (0.44) | NAAALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958518-B | Heterocyclyl pyridyl pyrazoles/heterocyclyl pyrimidines base pyrazoles | 拜耳知识产权有限责任公司 | 2017-07-04 | — | — | CN | disclosed |