Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675088 | 0.86 | LOXL2 (0.64) | HPGDLOXL2MAPK9MAPK10CYP1A2 | |
| SCHEMBL11515131 | 0.80 | MAPK9 (0.55) | HPGDLOXL2MAPK9MAPK10CYP1A2 | |
| SCHEMBL16383316 | 0.79 | HPGD (0.58) | HPGDLOXL2MAPK9MAPK10CYP1A2 | |
| SCHEMBL29971249 | 0.79 | HPGD (0.58) | HPGDLOXL2MAPK9MAPK10CYP1A2 | |
| SCHEMBL2146969 | 0.79 | LOXL2 (0.66) | HPGDLOXL2CYP1A2HSD17B10CYP2C19 | |
| SCHEMBL10351068 | 0.79 | HPGD (0.58) | HPGDLOXL2MAPK9MAPK10CYP1A2 | |
| SCHEMBL62420 | 0.79 | LOXL2 (0.66) | HPGDLOXL2CYP1A2HSD17B10CYP2C19 | |
| SCHEMBL20072395 | 0.76 | LOXL2 (0.62) | HPGDLOXL2MAPK9MAPK10CYP1A2 | |
| SCHEMBL5851278 | 0.76 | HPGD (0.69) | HPGDLOXL2CYP1A2HSD17B10CYP2C19 | |
| SCHEMBL8413104 | 0.76 | HPGD (0.54) | HPGDLOXL2MAPK9MAPK10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892880-A | A kind of synthetic method of 2- (1- hydroxy-naphthyls)-benzopyrene zinc | 西安瑞联新材料股份有限公司 | 2017-06-27 | — | — | CN | disclosed |