Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 7/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514240 | 0.80 | MAPK9 (0.52) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL28158591 | 0.80 | HPGD (0.58) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL11516409 | 0.79 | LOXL2 (0.57) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL9675088 | 0.78 | LOXL2 (0.64) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL7400010 | 0.77 | HPGD (0.59) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL21694384 | 0.76 | MAPK9 (0.48) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL7396493 | 0.74 | MAPK10 (0.64) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL27943317 | 0.74 | HPGD (0.59) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL9455568 | 0.73 | MAPK9 (0.58) | MAPK9MAPK10HPGDLOXL2ALOX5 | |
| SCHEMBL7390085 | 0.73 | MAPK10 (0.69) | MAPK9MAPK10HPGDLOXL2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146712-A | PROCESS FOR THE MANUFACTURE OF COUMARIN DYES | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | disclosed |
| US-4113718-A | Basic azo dyes | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-4064136-A | FROM A NITRILE, AN ALCOHOL AND ORTHO-SUBSTITUTED AROMATIC AMINE | CIBA-GEIGY AG (CH) | 1977-12-20 | — | — | US | disclosed |