Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 6/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442655 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2METNAMPT | |
| SCHEMBL28250308 | 0.80 | ALDH1A1 (0.66) | PDE10AALDH1A1LMNASMN1; SMN2MET | |
| SCHEMBL27824234 | 0.80 | MET (0.53) | PDE10AALDH1A1SMN1; SMN2METNPC1 | |
| SCHEMBL12048987 | 0.77 | MET (0.72) | MET | |
| SCHEMBL28254153 | 0.77 | MET (0.55) | PDE10AALDH1A1SMN1; SMN2METNPC1 | |
| SCHEMBL27988345 | 0.77 | MET (0.55) | PDE10AALDH1A1SMN1; SMN2METNPC1 | |
| SCHEMBL28158703 | 0.77 | NPC1 (0.46) | PDE10AALDH1A1SMN1; SMN2METNPC1 | |
| SCHEMBL28050970 | 0.77 | PDE10A (0.55) | PDE10AALDH1A1METNPC1POLB | |
| SCHEMBL27860197 | 0.76 | MET (0.49) | PDE10AALDH1A1SMN1; SMN2METNPC1 | |
| SCHEMBL4049830 | 0.75 | ALDH1A1 (0.46) | PDE10AALDH1A1LMNASMN1; SMN2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209453-B | The quinolyl conditioning agent of the methylene connection of ROR γ T | 詹森药业有限公司 | 2017-06-20 | — | — | CN | disclosed |