Quinoline

Quinoline

SCHEMBL28159259

Oc1nccc2ccccc12.c1ccc2ncccc2c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
CYP3A4 P08684 2/20 0.52
CASP1 P29466 2/20 0.46
MEN1 O00255 1/20 0.46
CASP7 P55210 1/20 0.46
KMT2A Q03164 1/20 0.46
PLAU P00749 2/20 0.44
NCF1 P14598 2/20 0.44
CYP2A6 P11509 1/20 0.44
F12 P00748 1/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
BACE1 P56817 1/20 0.44
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.42
PLG P00747 1/20 0.41
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58112 0.87 PLAU (0.56) ALDH1A1CYP3A4KMT2APLAUNCF1
Hydrochloric Acid SCHEMBL27487030 0.85 PLAU (0.54) ALDH1A1CYP3A4KMT2APLAUNCF1
SCHEMBL20787979 0.85 PLAU (0.54) ALDH1A1CYP3A4KMT2APLAUNCF1
Hydrochloric Acid SCHEMBL28313520 0.83 PLAU (0.52) ALDH1A1CYP3A4KMT2APLAUNCF1
Phenanthrene SCHEMBL28062390 0.81 ALDH1A1 (0.77) ALDH1A1CYP3A4CASP1MEN1CASP7
Triphenylene SCHEMBL28084439 0.80 ALDH1A1 (0.85) ALDH1A1CYP3A4CASP1MEN1CASP7
1-Naphthol SCHEMBL27401651 0.80 ALDH1A1 (0.63) ALDH1A1CYP3A4CASP1MEN1CASP7
Quinoline SCHEMBL28103672 0.80 ALDH1A1 (0.63) ALDH1A1CYP3A4CASP1MEN1CASP7
Phenanthrene SCHEMBL28090206 0.79 ALDH1A1 (0.74) ALDH1A1CYP3A4CASP1MEN1CASP7
1-Naphthol SCHEMBL28823427 0.79 ALDH1A1 (0.61) ALDH1A1CYP3A4CASP1MEN1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110400884-A Organic luminescent device and its manufacturing method SAMSUNG DISPLAY CO LTD 2019-11-01 CN disclosed
CN-110391351-A Organo-metallic compound and organic light emitting apparatus comprising the organo-metallic compound 三星显示有限公司 2019-10-29 CN disclosed
CN-109545932-A Light emitting diode 三星显示有限公司 2019-03-29 CN disclosed
CN-109216570-A Organic luminescent device 三星电子株式会社 2019-01-15 CN disclosed
CN-107814800-A Condensed-cyclic compound and the organic luminescent device for including it 三星显示有限公司 2018-03-20 CN disclosed
CN-107663191-A Polycyclic compound and the organic light emitting apparatus including the polycyclic compound 三星显示有限公司 2018-02-06 CN disclosed
CN-107359257-A Organic light emitting apparatus 三星显示有限公司 2017-11-17 CN disclosed
CN-106920896-A Organic luminescent device 三星显示有限公司 2017-07-04 CN disclosed
CN-106898702-A Organic light emitting apparatus 三星显示有限公司 2017-06-27 CN disclosed