Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | F12 | P00748 | 1/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27487030 | 0.98 | PLAU (0.54) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL20787979 | 0.98 | PLAU (0.54) | PLAUCYP2A6F12NCF1NOS3 | |
| Hydrochloric Acid SCHEMBL28313520 | 0.96 | PLAU (0.52) | PLAUCYP2A6F12NCF1NOS3 | |
| Pyrogallol SCHEMBL27753328 | 0.88 | CYP1A2 (0.52) | PLAUCYP2A6F12NCF1NOS3 | |
| Quinoline SCHEMBL28159259 | 0.87 | ALDH1A1 (0.61) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL13863867 | 0.83 | CYP3A4 (0.61) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL8346122 | 0.83 | PLAU (0.49) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL27757450 | 0.82 | PLAU (0.41) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL3973736 | 0.81 | PARP1 (0.66) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL31388387 | 0.80 | PLAU (0.41) | PLAUCYP2A6F12NCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5262 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4592399-B1 | COMPOSITIONS, KITS AND METHODS FOR ISOLATING TARGET POLYNUCLEOTIDES | DNAE DIAGNOSTICS LTD (GB) | 2026-03-11 | — | — | EP | claimed |
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | claimed |
| WO-2025149479-A1 | SYNTHESIS OF MODIFIED NUCLEOSIDE TRIPHOSPHATES | ROCHE DIAGNOSTICS GMBH (DE) | 2025-07-17 | — | — | WO | claimed |
| WO-2025021115-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海闻耐医药科技有限公司 | 2025-01-30 | — | — | WO | claimed |
| CN-119059964-A | Novel N-CF3 imide nitrogen heterocyclic compound and preparation method thereof | 浙江大学衢州研究院 | 2024-12-03 | — | — | CN | claimed |
| US-20240199701-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-06-20 | — | — | US | claimed |
| CN-118159549-A | Immunomodulators | 百时美施贵宝公司 | 2024-06-07 | — | — | CN | claimed |
| US-20240182460-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION | 2024-06-06 | — | — | US | claimed |
| WO-2024097172-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2024-05-10 | — | — | WO | claimed |
| EP-4090768-B1 | COMPOSITIONS, KITS AND METHODS FOR ISOLATING TARGET POLYNUCLEOTIDES | DNAE DIAGNOSTICS LTD (GB) | 2024-03-13 | — | — | EP | claimed |
| EP-0113910-B1 | ISOCARBOSTYRIL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-10-11 | — | — | EP | claimed |
| EP-0165110-B1 | OPTICALLY ACTIVE ISOCARBOSTYRIL DERIVATIVES AND A METHOD OF PREPARING THE SAME | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-12-28 | — | — | EP | claimed |
| EP-0073875-B1 | AZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1988-09-07 | — | — | EP | claimed |
| EP-0252721-A1 | 4-Nitrogen substituted isoquinolinol compounds having cardiotonic, phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-01-13 | — | — | EP | claimed |
| US-4659833-A | FOUR OPTICAL ISOMERS OF 1-(2'-(O-METHOXYPHENYL)-1'-METHYLETHYLAMINO)-3-(4\"-ISOCARBOSTYRILOXY)-2 -PROPANOL ISOLATED BY LIQUID CHROMATOGRAPHY | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| EP-0165110-A1 | Optically active isocarbostyril derivatives and a method of preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-12-18 | — | — | EP | claimed |
| EP-0113910-A1 | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1984-07-25 | — | — | EP | claimed |
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | claimed |
| US-4209467-A | COBALT COMPLEX CATALYST | DAICEL LTD. (JP) | 1980-06-24 | — | — | US | claimed |
| US-4043992-A | Method for preparing acylated products | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1977-08-23 | — | — | US | claimed |