Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL28159296

CC(C)=CC=O.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Methyl-(E)-2-Butenal SCHEMBL16862200 0.78 ALDH1A1 (0.43) ALDH1A1
3-Methyl-(E)-2-Butenal SCHEMBL250376 0.78
SCHEMBL5843517 0.76
SCHEMBL5843527 0.76
3-Methyl-(E)-2-Butenal SCHEMBL6364571 0.74
3-Methyl-(E)-2-Butenal SCHEMBL28327622 0.74
3-Methyl-(E)-2-Butenal SCHEMBL28076322 0.74
Trichloroacetic Acid SCHEMBL2472230 0.74 TSHR (0.77) ALDH1A1TP53TSHR
Trichloroacetic Acid SCHEMBL3952041 0.74 TSHR (0.77) ALDH1A1TP53TSHR
3-Methyl-(E)-2-Butenal SCHEMBL27957860 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008344-B Bruton's tyrosine kinase inhibitor 辉瑞公司 2017-07-25 CN disclosed