SCHEMBL2815936

SCHEMBL2815936

CC(=C\Oc1ccc2[nH]ccc2c1)/C(=N/c1ccccc1)Sc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.37
PTK6 Q13882 2/20 0.36
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
PRKCQ Q04759 1/20 0.33
MAOB P27338 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
ESR1 P03372 1/20 0.31
KDR P35968 1/20 0.31
NOTUM Q6P988 1/20 0.31
CYP2A6 P11509 1/20 0.31
AHR P35869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2815937 1.00 MAOA (0.37) MAOAPTK6NPC1MAPTRAB9A
SCHEMBL12850952 0.80 NOS3 (0.37) MAPTRAB9A
SCHEMBL2811138 0.80 NOS3 (0.37) MAPTRAB9A
SCHEMBL2811139 0.80 NOS3 (0.37) MAPTRAB9A
SCHEMBL12851032 0.80 CYP1A2 (0.36) MAPTCYP1A2CYP3A4CYP2C19SLC6A4
SCHEMBL2808724 0.80 CYP1A2 (0.36) MAPTCYP1A2CYP3A4CYP2C19SLC6A4
SCHEMBL2808720 0.80 CYP1A2 (0.36) MAPTCYP1A2CYP3A4CYP2C19SLC6A4
SCHEMBL2809811 0.78 NOS3 (0.33) CYP1A2CYP2C19GAA
SCHEMBL2813104 0.78 NOS3 (0.40) NPC1MAPTRAB9AGAA
SCHEMBL12851109 0.78 NOS3 (0.33) CYP1A2CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 MAOA 929/4885PTK6 3868/4885NPC1 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.