Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 9/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 9/20 | 0.52 |
| ▸ | CLK1 | P49759 | 8/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265869 | 0.77 | DYRK1A (0.55) | DYRK1ADYRK1BCLK1CA2HSD17B1 | |
| SCHEMBL31573206 | 0.74 | ALDH1A1 (0.45) | CLK1CA2MAPTHPGDGAA | |
| SCHEMBL11827 | 0.74 | DYRK1A (0.56) | DYRK1ADYRK1BCLK1CA2HSD17B1 | |
| SCHEMBL29698853 | 0.74 | HSP90AA1 (0.39) | DYRK1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6823688 | 0.74 | HSP90AA1 (0.39) | DYRK1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2040041 | 0.74 | CYP2A6 (0.38) | CYP1A2HTTMAPTHPGDGAA | |
| SCHEMBL18935983 | 0.74 | DYRK1A (0.52) | DYRK1ADYRK1BCLK1CA2HSD17B1 | |
| SCHEMBL28159356 | 0.74 | CA2 (0.54) | CA2 | |
| SCHEMBL2150129 | 0.73 | HSP90AA1 (0.30) | — | |
| SCHEMBL17010993 | 0.72 | HSP90AA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001281-A | Substituted benzothiophene radical derivative is used as the GPR40 activators for treating type ii diabetes | 詹森药业有限公司 | 2017-08-01 | — | — | CN | disclosed |