Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808520 | 0.85 | DPP7 (0.56) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL5434986 | 0.84 | CYP2D6 (0.38) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL4317858 | 0.81 | DPP7 (0.38) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL6191507 | 0.81 | DPP7 (0.38) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL4317849 | 0.81 | DPP7 (0.38) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL27220654 | 0.81 | TP53 (0.47) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL20358148 | 0.81 | GNAI3 (0.40) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL28290410 | 0.80 | ALDH1A1 (0.51) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| Hydrochloric Acid SCHEMBL30299029 | 0.79 | TP53 (0.46) | GNAI3GNAO1GNAI1ALDH1A1RRM1 | |
| SCHEMBL27207965 | 0.77 | TDP1 (0.59) | EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |
| CN-105753872-B | Two spiropiperidines or spiropyrrolidines derivatives | 第三共株式会社 | 2017-11-17 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |