Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420556 | 0.86 | SMN1; SMN2 (0.56) | KDM4ERAB9ANPC1SMN1; SMN2PSMB5 | |
| SCHEMBL9911459 | 0.86 | SMN1; SMN2 (0.56) | KDM4ERAB9ANPC1SMN1; SMN2PSMB5 | |
| Hydrochloric Acid SCHEMBL27788898 | 0.84 | SMN1; SMN2 (0.55) | KDM4ERAB9ANPC1SMN1; SMN2PSMB5 | |
| SCHEMBL9607087 | 0.82 | LONP1 (0.55) | KDM4ERAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL30060560 | 0.80 | PSMB5 (0.60) | KDM4ERAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL27843558 | 0.79 | ADORA3 (0.55) | KDM4ERAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL15145688 | 0.79 | KDM4E (0.52) | KDM4ERAB9ANPC1SMN1; SMN2PSMB5 | |
| SCHEMBL8293294 | 0.78 | KDM4E (0.58) | KDM4ERAB9ANPC1SMN1; SMN2PSMB5 | |
| SCHEMBL9607089 | 0.78 | LONP1 (0.58) | KDM4ERAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL13127955 | 0.78 | LONP1 (0.58) | KDM4ERAB9ANPC1SMN1; SMN2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069514-A | Antimicrobial compound and application thereof | 结核病药物开发全球联盟公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |