SCHEMBL28159682

SCHEMBL28159682

NCC1(c2ccccc2)CO1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.50
MAOA P21397 3/20 0.50
TAAR1 Q96RJ0 1/20 0.50
DPP4 P27487 2/20 0.47
GRIN1 Q05586 3/20 0.41
GRIN2A Q12879 3/20 0.41
HTR2A P28223 2/20 0.37
HTR2C P28335 2/20 0.37
HTR2B P41595 2/20 0.37
EGFR P00533 1/20 0.37
KDM1A O60341 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7833714 0.85 HTR1A (0.52) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL8951708 0.77 GAA (0.39) MAOBMAOATAAR1EGFRKDM1A
SCHEMBL2764548 0.77 HTR1A (0.39) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL6493723 0.77 MEN1 (0.40) MAOBMAOATAAR1EGFR
SCHEMBL8766885 0.77 GAA (0.39) MAOBMAOATAAR1EGFRKDM1A
SCHEMBL6493726 0.77 MEN1 (0.40) MAOBMAOATAAR1EGFR
SCHEMBL6494304 0.76 MAOA (0.43) MAOBMAOAEGFRKDM1A
SCHEMBL6494298 0.76 MAOA (0.43) MAOBMAOAEGFRKDM1A
SCHEMBL11702282 0.76 HTR1A (0.38) MAOBMAOATAAR1DPP4GRIN1
SCHEMBL8806111 0.74 CHRM2 (0.38) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104277194-B Polyurethane resin composition and polyurethane composition prepared therefrom 科思创德国股份有限公司 2018-11-30 CN disclosed
CN-105503559-B A kind of method for preparing black nightshade aldehyde 上海应用技术学院 2017-06-23 CN disclosed