Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3794549 | 1.00 | FAAH (0.40) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL30324569 | 1.00 | FAAH (0.40) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL27681955 | 0.97 | FAAH (0.39) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL27627328 | 0.97 | FAAH (0.39) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL6909668 | 0.97 | FAAH (0.39) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL21924385 | 0.97 | FAAH (0.39) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL29019101 | 0.94 | FAAH (0.37) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL5898930 | 0.91 | FAAH (0.36) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL29019087 | 0.91 | FUCA1 (0.39) | FAAHALDH1A1TSHRFFAR3CES1 | |
| Trifluoroacetic Acid SCHEMBL31031817 | 0.90 | FAAH (0.42) | FAAHALDH1A1TSHRFFAR3CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117761207-A | Method for detecting impurities of tedizolid phosphate and tedizolid phosphate isomer for injection | 重庆常捷医药有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116925023-A | Improved synthesis of 2-perfluoroalkyl-4H-pyran-4-one derivatives | 江苏桐孚高新材料有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116041177-A | Method for preparing R-3-hydroxybutyrate by degrading poly-3-hydroxybutyrate by recycling alcohol-trifluoroacetic acid solvent system | 东莞理工学院 | 2023-05-02 | — | — | CN | claimed |
| CN-115993417-A | Method for detecting R-isomer in mitiglinide calcium or preparation thereof | 北京四环科宝制药股份有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-115541734-A | Method for determining protected amino acid enantiomer by normal phase chromatography | 南京锐志生物医药有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-110583762-B | Oligosaccharide preservative for inhibiting fruit softening and relieving mechanical damage, and use method and application thereof | 天津科技大学 | 2022-10-28 | — | — | CN | claimed |
| CN-115144498-A | Method for detecting content of enantiomers in acetylcysteine and acetylcysteine particles | 浙江金华康恩贝生物制药有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-114907024-A | Surface coating process for glass product | 南通瀚佳诺玻璃工艺品有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-114200034-A | Analysis method of vernakalant related substances | 上海旭东海普药业有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-112778260-A | Blueberry anthocyanin-rich extract and preparation method thereof | 齐鲁工业大学 | 2021-05-11 | — | — | CN | claimed |
| CN-107219312-B | A method of detection Tedizolid Phosphate isomer impurities | 南京优科生物医药研究有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-110204498-A | A method of it efficiently synthesizes and dislikes La Geli intermediate | 奥锐特药业股份有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-108426956-A | A kind of method of impurity F in Captopril by HPLC | 郑州泰丰制药有限公司 | 2018-08-21 | — | — | CN | claimed |
| CN-108226329-A | The liquid phase chromatography analytical method of L- prolineamides | 浙江天宇药业股份有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-108031452-A | Porous adsorbent that surface is expressed by polycarboxylic acid and its preparation method and application | 同济大学 | 2018-05-15 | — | — | CN | claimed |
| CN-105424828-B | The method of enantiomter content in detection levocarnitine | 山东齐都药业有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-105424828-A | Method for detecting content of enantiomer in levocarnitine | SHANDONG QIDU PHARMACEUTICAL | 2016-03-23 | — | — | CN | claimed |
| CN-101693718-B | Ester derivative containing thienopyridine and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2011-10-19 | — | — | CN | claimed |
| CN-101693718-A | Ester derivative containing thienopyridine and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2010-04-14 | — | — | CN | claimed |
| CN-101243081-A | Pyrido[2,3-d]pyrimidine-2,4-diamine compounds as PTP1B inhibitors | HOFFMANN LA ROCHE (CH) | 2008-08-13 | — | — | CN | claimed |