Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.75 |
| ▸ | CA1 | P00915 | 13/20 | 0.68 |
| ▸ | CA9 | Q16790 | 12/20 | 0.68 |
| ▸ | CA12 | O43570 | 10/20 | 0.68 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107398 | 0.89 | SOS1 (0.70) | CA2CA1CA9CA12SOS1 | |
| SCHEMBL183959 | 0.87 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| Hydrochloric Acid SCHEMBL3536600 | 0.84 | CA2 (0.95) | CA2CA1CA9CA12CA4 | |
| SCHEMBL27550714 | 0.82 | EGFR (0.58) | CA2CA1CA9CA12SOS1 | |
| SCHEMBL671553 | 0.81 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| SCHEMBL671915 | 0.81 | CA2 (0.74) | CA2CA1CA9CA12SOS1 | |
| SCHEMBL8023015 | 0.81 | CA1 (0.67) | CA2CA1CA9CA12SOS1 | |
| SCHEMBL27497103 | 0.79 | CA1 (0.75) | CA2CA1CA9CA12SOS1 | |
| SCHEMBL28323146 | 0.79 | CA2 (0.75) | CA2CA1CA9CA12SOS1 | |
| SCHEMBL12278421 | 0.78 | SOS1 (0.58) | CA2CA1CA9CA12SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033043-B | N- replaces benzenesulfonyl-substituted benzene formyl amine compound and its prepares the purposes of drug | 中国人民解放军第二军医大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-107033043-A | N- replaces benzenesulfonyl-substituted benzene formyl amine compound and its prepares the purposes of medicine | 中国人民解放军第二军医大学 | 2017-08-11 | — | — | CN | disclosed |