SCHEMBL8023015

SCHEMBL8023015

NS(=O)(=O)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.67
CA2 P00918 13/20 0.67
CA9 Q16790 12/20 0.67
CA12 O43570 11/20 0.67
PTPN7 P35236 1/20 0.65
CA4 P22748 2/20 0.62
CA6 P23280 2/20 0.62
CA5A P35218 2/20 0.62
CA7 P43166 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CA5B Q9Y2D0 2/20 0.62
CA3 P07451 1/20 0.62
PLA2G7 Q13093 1/20 0.62
CA13 Q8N1Q1 1/20 0.62
SOS1 Q07889 3/20 0.61
PIM1 P11309 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.56
ALDH1A1 P00352 1/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28107398 0.91 SOS1 (0.70) CA1CA2CA9CA12CA4
Diphenylamine SCHEMBL27603173 0.90 CA2 (0.65) CA1CA2CA9CA12PTPN7
Diphenylamine SCHEMBL17958823 0.88 CA12 (0.67) CA1CA2CA9CA12PTPN7
Pyrimidine SCHEMBL28325080 0.88 CA1 (0.57) CA1CA2CA9CA12PTPN7
SCHEMBL28884752 0.87 CA2 (0.67) CA1CA2CA9CA12PTPN7
SCHEMBL618161 0.85 SNCA (0.71) CA1CA2CA9CA12PTPN7
SCHEMBL28217410 0.85 CA2 (0.65) CA1CA2CA9CA12CA4
Hydrochloric Acid SCHEMBL11027004 0.85 CA2 (0.65) CA1CA2CA9CA12PTPN7
SCHEMBL671915 0.83 CA2 (0.74) CA1CA2CA9CA12CA4
SCHEMBL28746782 0.81 LMNA (0.70) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118880537-A Anti-biological adhesion warp knitting net product and preparation method thereof 山东海工科技有限公司 2024-11-01 CN claimed
CN-118546213-A Tumor targeting polypeptide and application 南方医科大学深圳医院 2024-08-27 CN claimed
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2024-05-30 US claimed
CN-111912802-A Method for detecting nitrite nitrogen by spectrophotometry 潍坊市生态环境局寿光分局 2020-11-10 CN claimed
CN-110468497-A A kind of antibacterial composite fabric and its manufacturing method FUJIAN BAIKAI WARP KNITTING IND CO LTD 2019-11-19 CN claimed
CN-110468463-A A kind of high-end knitting fabric and its processing method FUJIAN BAIKAI WARP KNITTING IND CO LTD 2019-11-19 CN claimed
CN-110409012-A A kind of antibiotic polyester fiber and preparation method thereof FUJIAN BILLION POLYFIBER IND CO LTD 2019-11-05 CN claimed
CN-110344134-A A kind of modified polyester fibre and its production method 福建百宏聚纤科技实业有限公司 2019-10-18 CN claimed
CN-107033043-B N- replaces benzenesulfonyl-substituted benzene formyl amine compound and its prepares the purposes of drug 中国人民解放军第二军医大学 2019-04-30 CN claimed
CN-107635986-A Substituted quinoxaline derivatives 赛尔维他股份公司 2018-01-26 CN claimed
CN-104419504-A Washable machine oil NANTONG HENGDING HEAVY MACHINE CO LTD 2015-03-18 CN claimed
CN-101898985-B N-substituted benzenesulfonyl-substituted benzamides small molecular inhibitor of Bcl-2 protein and application thereof UNIV PLA 2ND MILITARY MEDICAL 2014-05-28 CN claimed
CN-103420891-A Triphosgene method for synthesizing benzene sulphanilamide, intermediate of glimepiride, drug for Type ii Diabetes Mellitus NANTONG HUAFENG CHEMICAL CO 2013-12-04 CN claimed
CN-101253221-B A chain-end functionalized poly(ethylene oxide) and process for the preparation of a nano-sized transition metal or metal salt using the same YOUL CHON CHEMICAL CO LTD 2013-03-20 CN claimed
CN-102582184-A Polyamides semi-cristallins souples ARKEMA FRANCE 2012-07-18 CN claimed
CN-101898985-A N-substituted benzenesulfonyl-substituted benzamides small molecular inhibitor of Bcl-2 protein and application thereof UNIV PLA 2ND MILITARY MEDICAL 2010-12-01 CN claimed
CN-101253221-A A chain-end functionalized poly(ethylene oxide) and process for the preparation of a nano-sized transition metal or metal salt using the same YOUL CHON CHEMICAL CO LTD (KR) 2008-08-27 CN claimed
CN-1127952-C Anticancer medicine composition KONG QINGZHONG (CN) 2003-11-19 CN claimed
CN-1335839-A Bis-sulfonamides ACTELION PHARMACEUTICALS LTD (CH) 2002-02-13 CN claimed
CN-1275377-A Anticancer medicine composition KONG QINGZHONG (CN) 2000-12-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME PPM1A, PPP2CA, PPP3CA CA1 1360/4885CA2 2400/4885CA9 4321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.