SCHEMBL28160686

SCHEMBL28160686

Oc1ccccc1OCCCN1CCN=C1Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
HRH1 P35367 7/20 0.44
DRD4 P21917 6/20 0.44
DRD3 P35462 5/20 0.44
DRD1 P21728 5/20 0.44
DRD5 P21918 5/20 0.44
DRD2 P14416 4/20 0.44
JAK2 O60674 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10691316 0.77 CYP1A2 (0.82) CYP1A2CYP2D6DRD4HTR1DHTR1B
SCHEMBL23121057 0.76 CYP1A2 (0.70) CYP1A2CYP2D6DRD4HTR1DHTR1B
SCHEMBL17965485 0.76 CYP1A2 (0.74) CYP1A2CYP2D6DRD4LMNAHTR1D
Hydrochloric Acid SCHEMBL251996 0.74 CYP1A2 (0.72) CYP1A2CYP2D6DRD4LMNAHTR1D
SCHEMBL13990186 0.74 CYP1A2 (1.00) CYP1A2CYP2D6DRD4HTR1DHTR1B
SCHEMBL10690989 0.74 CYP1A2 (0.67) CYP1A2CYP2D6DRD4HTR1DHTR1B
SCHEMBL11190221 0.73 CYP1A2 (0.74) CYP1A2CYP2D6DRD4LMNAHTR1D
SCHEMBL11135471 0.71 CYP1A2 (0.71) CYP1A2CYP2D6DRD4LMNAGAA
SCHEMBL1837432 0.67 LMNA (0.64) DRD4DRD3DRD1DRD2JAK2
SCHEMBL27615655 0.67 L3MBTL1 (0.53) CYP1A2CYP2D6DRD4DRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797623-B Resin curing agent and one-component epoxy resin composition 味之素株式会社 2018-09-25 CN disclosed
CN-107428939-A Resin composition, adhesive and sealant 纳美仕有限公司 2017-12-01 CN disclosed
CN-107428781-A Mercaptoethyl glycoluril compounds and its application 四国化成工业株式会社 2017-12-01 CN disclosed
CN-105458161-B A kind of powdered mold release agents composition 浙江龙游展宇有机玻璃有限公司 2017-08-15 CN disclosed
CN-107011514-A Light and heat hardening resin composition 味之素株式会社 2017-08-04 CN disclosed